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Estimation of residential radon exposure and definition of Radon Priority Areas based on expected lung cancer incidence
Environment International ( IF 10.3 ) Pub Date : 2018-02-24 , DOI: 10.1016/j.envint.2018.02.025
J. Elío , Q. Crowley , R. Scanlon , J. Hodgson , L. Zgaga

Radon is a naturally occurring gas, classified as a Class 1 human carcinogen, being the second most significant cause of lung cancer after tobacco smoking. A robust spatial definition of radon distribution in the built environment is therefore essential for understanding the relationship between radon exposure and its adverse health effects on the general population. Using Ireland as a case study, we present a methodology to estimate an average indoor radon concentration and calculate the expected radon-related lung cancer incidence. We use this approach to define Radon Priority Areas at the administrative level of Electoral Divisions (EDs).

Geostatistical methods were applied to a data set of almost 32,000 indoor radon measurements, sampled in Ireland between 1992 and 2013. Average indoor radon concentrations by ED range from 21 to 338 Bq m−3, corresponding to an effective dose ranging from 0.8 to 13.3 mSv y−1 respectively. Radon-related lung cancer incidence by ED was calculated using a dose-effect model giving between 15 and 239 cases per million people per year, depending on the ED. Based on these calculations, together with the population density, we estimate that of the approximately 2,300 lung cancer cases currently diagnosed in Ireland annually, about 280 may be directly linked to radon exposure. This figure does not account for the synergistic effect of radon exposure with other factors (e.g. tobacco smoking), so likely represents a minimum estimate. Our approach spatially defines areas with the expected highest incidence of radon-related lung cancer, even though indoor radon concentrations for these areas may be moderate or low. We therefore recommend that both indoor radon concentration and population density by small area are considered when establishing national radon action plans.



中文翻译:

根据预期的肺癌发病率估算居民ra暴露量并确定on优先区域

on是一种自然产生的气体,被归类为1类人类致癌物,是仅次于吸烟的第二大肺癌致因。因此,对建筑环境中ra分布的稳健空间定义对于理解ra暴露及其对一般人群的不良健康影响之间的关系至关重要。以爱尔兰为例,我们提出了一种估算室内平均indoor浓度并计算预期的expected相关肺癌发病率的方法。我们使用这种方法在选举部门(EDs)的管理级别上定义Radon优先区域。

地统计学方法应用于1992年至2013年间在爱尔兰采样的近32,000个室内ra测量数据集。按ED计算的平均室内ra浓度范围为21到338 Bq m -3,相当于有效剂量为0.8到13.3 mSv y -1分别。ED所致的相关肺癌发病率是通过剂量效应模型计算得出的,该模型每年得出的百万分之十五至239例病例,这取决于ED。基于这些计算,再加上人口密度,我们估计在爱尔兰目前每年诊断出的约2300例肺癌病例中,约有280例可能与ra暴露直接相关。该数字未考虑exposure暴露与其他因素(例如吸烟)的协同效应,因此可能代表了最低估计值。我们的方法在空间上定义了与of相关的肺癌预期最高发病率的区域,即使这些区域的室内ra浓度可能适中或较低。

更新日期:2018-02-24
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