In recent years, research has focused on the development of smart nanocarriers that can respond to specific stimuli. Among the various stimuli-responsive platforms for cancer therapy, near-infrared (NIR) light (700–1000 nm)-responsive nanocarriers have gained considerable interest because of their deeper tissue penetration capacity, precisely controlled drug release, and minimal damage towards normal tissues. In this review, we outline various therapeutic applications of NIR-responsive nanocarriers in drug delivery, photothermal therapy (PTT), photodynamic therapy (PDT), and bioimaging. We also highlight recent trends towards NIR-responsive combinatorial therapy and multistimuli-responsive nanocarriers for improving therapeutic outcomes.

近年来，研究集中在可以响应特定刺激的智能纳米载体的开发上。在用于癌症治疗的各种刺激响应平台中，近红外（NIR）光（700–1000 nm）响应纳米载体因其更深的组织穿透能力，精确控制的药物释放以及对正常组织的损害最小而引起了人们的极大兴趣。 。在这篇综述中，我们概述了近红外响应纳米载体在药物输送，光热疗法（PTT），光动力疗法（PDT）和生物成像中的各种治疗应用。我们还重点介绍了近红外向响应组合疗法和多刺激响应纳米载体的最新趋势，以改善治疗效果。