Background

Noise exposure increases blood pressure and peripheral vascular resistance in both genders in an experimental setting, as previously reported by the authors.

Objectives

The aim of this re-analysis was to present the minute-by-minute timeline of blood pressure changes and hemodynamic events provoked by traffic noise in the young and healthy adults.

Methods

The experiment consisted of three 10-min phases: rest in quiet conditions before noise (Leq = 40 dBA), exposure to recorded road-traffic noise (Leq = 89 dBA), and rest in quiet conditions after noise (Leq = 40 dBA). Participants’ blood pressure, heart rate, and hemodynamic parameters (cardiac index and total peripheral resistance index) were concurrently measured with a thoracic bioimpedance device. The raw beat-to-beat data were collected from 112 participants, i.e., 82 women and 30 men, aged 19–32 years. The timeline of events was created by splitting each experimental phase into ten one-minute intervals (30 intervals in total). Four statistical models were fitted to answer the six study questions what is happening from one minute to another during the experiment.

Results

Blood pressure decreased during quiet phase before noise, increased in the first minute of noise exposure and then decreased gradually toward the end of noise exposure, and continued to decline to baseline values after noise exposure. The cardiac index showed a gradual decrease throughout the experiment, whereas total vascular resistance increased steadily during and after noise exposure.

Conclusions

The timeline of events in this 30-min experiment provides insight into the hemodynamic processes underlying the changes of blood pressure before, during and after noise exposure.

中文翻译：

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实验性噪声暴露期间的血压变化和血流动力学反应的时间线

背景

作者先前曾报道，在实验环境中，噪声暴露会增加男女的血压和外周血管阻力。

目标

这项重新分析的目的是介绍年轻人和健康成年人中因交通噪声引起的血压变化和血液动力学事件的每分钟时间表。

方法

该实验包括三个10分钟的阶段：在噪声（Leq = 40 dBA）之前安静的环境中休息，暴露于记录的道路交通噪声（Leq = 89 dBA）以及在噪声之后（Leq = 40 dBA）的安静状态中休息。使用胸腔生物阻抗仪同时测量参与者的血压，心率和血液动力学参数（心脏指数和总外周阻力指数）。原始的逐搏数据收集自112位参与者，即82位女性和30位男性，年龄在19-32岁之间。通过将每个实验阶段分为十个一分钟间隔（总共30个间隔）来创建事件的时间轴。拟合了四个统计模型，以回答这六个研究问题，即实验过程中从一分钟到另一分钟的情况。

结果

在噪声发生之前的安静阶段，血压降低，在噪声暴露的第一分钟内升高，然后在噪声暴露结束时逐渐降低，并在噪声暴露后继续下降至基线值。在整个实验过程中，心脏指数逐渐降低，而在暴露于噪声期间和之后，总的血管阻力逐渐增加。

结论

在这个30分钟的实验中，事件的时间线提供了深入了解噪音暴露前后，过程中和血压变化背后的血液动力学过程的信息。