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A miniaturized sorbent phase-based extraction device in the form of syringe filter holder using molecularly imprinted polymer as sorbent and its application to extract benzophenones
Journal of Chromatography A ( IF 3.8 ) Pub Date : 2018-02-22 , DOI: 10.1016/j.chroma.2018.02.039
Xiao Sun , Xin-yue Jiao , Jing Li , Li Xu

The molecularly imprinted polymer using 2,4-dihydroxybenzophenone as the template (DHBP-MIP) was synthesized via sacrificial support method. The DHBP-MIP was demonstrated to possess good adsorption capacity and selectivity towards benzophenones. Moreover, a miniaturized sorbent phase-based extraction device in the form of syringe filter holder using DHBP-MIP as the sorbent was proposed, and named as μ-SPE-SFH-MIP device. The μ-SPE-SFH-MIP device consisted of a reusable syringe filter holder, flexible amount of sorbent and a sub-microporous membrane, which could be conveniently connected to different driving forces, like syringe pump, solid-phase extraction device and peristaltic pump. It was successfully applied to extract five benzophenones from swimming pool water and human urine samples, combined with high performance liquid chromatograph-UV analysis, with detection limits of 0.12–0.68 μg L−1 and 0.21–1.05 μg L−1, respectively. The accuracy and precision of the analytes were in the range of 89.27%–113.35% for swimming pool water samples and 90.65%–108.00% for urine samples, with all the relative standard deviation values below 7.89%. The μ-SPE-SFH-MIP device was portable, cost-effective operational convenient and suitable for the small-size samples; moreover, with the MIP as the sorbent, it afforded additional high selectivity and sensitivity.



中文翻译:

基于分子印迹聚合物作为吸附剂的针筒式过滤器支架形式的基于吸附剂的微型化萃取装置及其在萃取二苯甲酮中的应用

通过牺牲支撑法合成了以2,4-二羟基二苯甲酮为模板的分子印迹聚合物(DHBP-MIP)。DHBP-MIP被证明具有良好的吸附能力和对二苯甲酮的选择性。此外,提出了一种使用DHBP-MIP作为吸附剂的针筒式过滤器支架形式的基于吸附剂相的小型化萃取装置,并将其命名为μ-SPE-SFH-MIP装置。μ-SPE-SFH-MIP设备由可重复使用的注射器过滤器支架,灵活量的吸附剂和亚微孔膜组成,可以方便地连接到不同的驱动力,例如注射器泵,固相萃取设备和蠕动泵。它已成功应用于从游泳池水和人体尿液样品中提取五种二苯甲酮,-1和0.21-1.05μgL -1。游泳池水样的分析物的准确性和精密度在89.27%–113.35%的范围内,尿液样本的分析物的准确性和精密度的范围在90.65%–108.00%的范围内,所有相对标准偏差值均低于7.89%。μ-SPE-SFH-MIP设备便于携带,具有成本效益,操作方便,适用于小尺寸样品;此外,使用MIP作为吸附剂,它还具有更高的选择性和灵敏度。

更新日期:2018-02-22
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