Diabetic nephropathy (DN) is a micro‐vascular complication of chronic diabetes. Sterol regulatory element binding protein1 (SREBP1) participation in the development of DN is reported. Oryzanol concentrate (OC) at 0.1% and 0.3% is tested for its antioxidant and hypolipidemic effects. The aim of the work is to study the involvement of OC in the amelioration of DN in STZ‐induced diabetic animal model.

中文翻译：

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谷维素浓缩物的降脂和抗氧化特性通过SREBP1下调而不是β氧化来减轻糖尿病性肾病

糖尿病肾病（DN）是慢性糖尿病的微血管并发症。据报道，甾醇调节元件结合蛋白1（SREBP1）参与了DN的发展。测试了0.1％和0.3％的谷维素浓缩物（OC）的抗氧化和降血脂作用。这项工作的目的是研究OC在STZ诱导的糖尿病动物模型中改善DN的作用。