Purpose

To present ophthalmic patient time-tradeoff vision utilities for quantifying vision-related quality-of-life when the fellow eye still has good vision. These utilities are important for performing reliable cost-utility analyses.

Design

Consecutive time-tradeoff vision utilities were obtained from ophthalmic patients with good vision (20/20–20/25) in one eye and vision ranging from 20/20 to no light perception in the fellow eye over a 15-year period from 2000 through 2014.

Participants

Five hundred eighty-six ophthalmic participant interviews from Wills Eye Hospital, New York Eye and Ear Hospital, and ophthalmology office practices in Pennsylvania and New Jersey.

Methods

Participants underwent a full ophthalmic examination, after which time-tradeoff vision utilities were obtained by personal interview by the authors using a standardized, validated instrument.

Main Outcome Measures

Time-tradeoff vision utilities.

Results

Mean time-tradeoff vision utilities were as follows in participants with good vision (20/20–20/25) in at least one eye and the following visions in the fellow eyes: no light perception, 0.79; counting fingers to light perception, 0.87; 20/200 to 20/400, 0.88; 20/60 to 20/100, 0.88; 20/30 to 20/50, 0.87; and 20/20 to 20/25, 0.94.

Conclusions

In people with good vision (20/20–20/25) in one eye, the associated mean time-tradeoff vision utility is a remarkably consistent 0.87 to 0.88 when vision in the fellow eye ranges from 20/30 to light perception. Vision of 20/20 to 20/25 in the fellow eye results in a significantly higher associated utility of 0.94 (P < 0.01), whereas vision of no light perception in the fellow eye results in a significantly lower utility of 0.079 (P < 0.01). These utilities are important for calculating reliable patient value (quality-adjusted life-year) gains in ophthalmic cost-utility analysis populations in which there is unilateral and bilateral disease involvement.

中文翻译：

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与单侧和双侧眼部疾病相关的视觉相关生活质量

目的

提出眼科患者时间权衡的视觉工具，以在另一只眼睛仍具有良好视力时量化与视觉有关的生活质量。这些实用程序对于执行可靠的成本-实用程序分析很重要。

设计

连续时间权衡的视力效用是从2000年至15年的15年内从一只眼睛具有良好视力（20 / 20–20 / 25）的眼科患者获得的，视力范围从20/20到另一只眼的无光感2014。

参加者

来自威尔斯眼科医院，纽约眼耳医院的586名眼科参加者访谈以及宾夕法尼亚州和新泽西州的眼科办公室实践。

方法

参与者进行了全面的眼科检查，之后作者通过使用标准化的，经过验证的仪器进行了个人访谈，获得了时间折衷的视觉工具。

主要观察指标

时间权衡的视觉工具。

结果

在至少一只眼睛具有良好视力（20 / 20–20 / 25）的参与者和另一只眼睛具有以下视力的参与者中，平均时间权衡的效用如下：无光感0.79；无视力0.79。数数手指以感知光线，为0.87；20/200至20 / 400，0.88；20/60至20 / 100，0.88；20/30至20 / 50，0.87；和20/20至20/25，即0.94。

结论

对于一只眼睛具有良好视力（20 / 20–20 / 25）的人，当另一只眼睛的视力范围为20/30到光线感知时，相关的平均时间折衷视觉效用非常一致，为0.87至0.88。另一只眼睛的视力为20/20至20/25会导致0.94的显着较高的关联效用（P <0.01），而另一只眼睛的无光感的视觉会导致0.079（P <0.01）的显着较低的效用）。这些实用程序对于计算涉及单侧和双侧疾病的眼科成本-效用分析人群中的可靠患者价值（质量调整生命年）收益至关重要。