A new 14-membered macrolactam natural product, fluvirucin B6 (1), was isolated from a marine-derived actinomycete, Nocardiopsis sp. CNQ-115, via HPLC-UV guided isolation. The chemical structure of 1 was elucidated by 1D and 2D NMR spectroscopic data analysis. Compound 1 showed a weak activity against Gram-positive bacteria, whereas it was inactive against Gram-negative bacteria.

中文翻译：

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Fluvirucin B6，一种新的大白内酰胺，从海洋衍生的诺卡氏菌属放线菌中分离出来。

从海洋来源的放线菌Nocardiopsis sp。分离出一种新的14元大环内酰胺天然产品fluvirucin B6（1）。CNQ-115，通过HPLC-UV引导分离。1D和2D NMR光谱数据分析阐明了1的化学结构。化合物1对革兰氏阳性细菌显示较弱的活性，而对革兰氏阴性细菌则没有活性。