The demand for manufactured products and the derivatives of nanomaterials and non essential metals continue to increase, and as a consequence their presence in fisheries and aquaculture has therefore become a major concern for the risks to which our environment is exposed. The bioaccumulation profile of binary compounds (Titanium dioxide nanoparticles and lead) and their effects on the feeding behaviour of copepods were assessed in a simplified food chain including, the freshwater alga Chlorella ellipsoides and the cyclopoids copepods sp. Our results indicated that Pb and TiO₂ NPs individually and mixed can be transferred from alga to copepods via dietary pathway. The highest bioconcentration factor (748.5) was recorded for Pb in the combined compounds (Pb15 + Ti16.5) μg L⁻¹ and the highest BCF (5.57) recorded for TiO₂ NPs was found in TiO₂ NPs (16.5) alone. Ingestion and filtration rate decreased significantly (p < 0.05) in all treatments. Analysis of variance (ANOVA) showed that the combination of these metals significantly (p < 0.05) decreased ingestion and filtration rate. In addition, the individual compounds and their combinations significantly (p < 0.05) increased carbohydrate and total lipid content. The antioxidant activities showed significant (p < 0.05) effect of Glutathione peroxidase (GPx), Glutathione reductase (GR), catalase (CAT) however, SOD and MDA were not significant (p > 0.05) in both single and binary treatments. The results demonstrate that the co-exposure of TiO₂ NPs and Pb inhibit the ingestion and filtration of microalgae by cyclopoid copepods sp. and also induce increase of carbohydrate, lipid; GPx, GR and CAT due to stress.

对制成品以及纳米材料和非必需金属衍生物的需求不断增加，因此，它们在渔业和水产养殖业中的存在已成为我们环境所面临风险的主要关注点。在简化的食物链中评估了二元化合物（二氧化钛纳米颗粒和铅）的生物蓄积特性及其对co足类动物摄食行为的影响，其中包括淡水藻类小球藻（Chlorella ellipsoides）和摆线体co足类藻（speopoids copepods sp）。我们的结果表明，Pb和TiO ₂ NPs单独或混合可以通过饮食途径从藻类转移到co足类动物中。合并的化合物（Pb15 + Ti16.5）中的Pb最高生物富集因子（748.5）μgL仅在TiO ₂ NP（16.5）中发现^-1和记录到的TiO ₂ NPs最高的BCF（5.57）。在所有处理中，摄入和过滤速率均显着降低（p <0.05）。方差分析（ANOVA）表明，这些金属的组合显着（p <0.05）降低了摄入和过滤速率。此外，单个化合物及其组合显着（p <0.05）增加了碳水化合物和总脂质含量。抗氧化剂活性显示出谷胱甘肽过氧化物酶（GPx），谷胱甘肽还原酶（GR），过氧化氢酶（CAT）的显着（p <0.05）效果，但是在单一和二元处理中SOD和MDA均不显着（p> 0.05）。结果表明，TiO ₂的共同暴露NPs和Pb抑制了类脂足pe足类sp摄入和过滤微藻。并导致碳水化合物，脂质增加；由于压力导致GPx，GR和CAT。