The semicrystalline poly(L-lactide) (PLLA) belongs to the materials with shape memory effect (SME) and as a bioresorbable and biocompatible polymer it have found many applications in medical and pharmaceutical field. Assessment of the SME impact on the polymer degradation profile plays crucial role in applications such as drug release systems or in regenerative medicine. Herein, the results of in vitro degradation studies of PLLA samples after SME full test cycle are presented. The samples were loaded and deformed in two manners: progressive and non-progressive. The performed experiments illustrate also influence of the material mechanical damages, caused e.g. during incorrect implantation of PLLA product, on hydrolytic degradation profile. Apparently, degradation profiles are significantly different for the material which was not subjected to the deformation and the deformed ones. The materials after deformation of 50% (in SME cycle) was characterized by non-reversible morphology changes. The effect was observed in deformed samples during the SME test which were carried out ten times.

半结晶聚（L-丙交酯）（PLLA）属于具有形状记忆效应（SME）的材料，并且作为可生物吸收和生物相容的聚合物，已在医学和制药领域中获得了许多应用。SME对聚合物降解曲线的影响评估在诸如药物释放系统或再生医学等应用中起着至关重要的作用。在此，提供了在SME完整测试周期后对PLLA样品进行体外降解研究的结果。样品以两种方式加载和变形：渐进式和非渐进式。进行的实验还说明了材料机械损伤（例如在错误植入PLLA产品期间引起的）对水解降解曲线的影响。显然，对于未发生变形的材料和未变形的材料，其降解曲线有显着差异。变形后50％（在SME循环中）的材料的特征是不可逆的形态变化。在SME测试期间变形样品中观察到了这种效果，该样品进行了十次。