Base‐Mediated Cyclization of 3‐[2‐(2‐Oxo‐2‐phenylethyl)‐1‐pyrrolidinyl]propanenitrile to 7‐Phenyl‐1,2,3,7,8,8a‐hexahydroindolizine‐6‐carbonitrile: What Lies Between?,European Journal of Organic Chemistry

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Base‐Mediated Cyclization of 3‐[2‐(2‐Oxo‐2‐phenylethyl)‐1‐pyrrolidinyl]propanenitrile to 7‐Phenyl‐1,2,3,7,8,8a‐hexahydroindolizine‐6‐carbonitrile: What Lies Between?
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2018-04-26 , DOI: 10.1002/ejoc.201701714
Garreth L. Morgans ₁ , Manuel A. Fernandes ₁ , Willem A. L. van Otterlo _{1,

2} , Joseph P. Michael ₁

Affiliation

Three intermediates formed during the base‐mediated conversion of the pyrrolidine‐containing keto‐nitrile into two diastereoisomers of the title indolizine were isolated and characterized.