The herbicide alachlor has been widely used in US agriculture since its introduction in 1969. Experimental animal studies show that alachlor causes tumors in vivo; however, few epidemiologic studies have examined associations with human cancer risk. We evaluated alachlor use and cancer incidence in the Agricultural Health Study, updating an earlier analysis that suggested associations with lymphohematopoietic cancers with an additional 540 142 person-years of follow-up and 5113 cancer cases.

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农业卫生研究中甲草胺的使用和癌症的发病率：最新分析

自从1969年引入除草剂甲草胺以来，该化合物已在美国农业中得到广泛应用。动物实验研究表明，甲草胺可在体内引起肿瘤。然而，很少有流行病学研究检查与人类癌症风险的关联。我们在《农业健康研究》中评估了甲草胺的使用和癌症的发生率，并更新了较早的分析，该分析表明与淋巴造血癌相关，另外有540 142人年的随访和5113例癌症病例。