Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy–Treated Human Immunodeficiency Virus–Infected Individuals,Clinical Infectious Diseases

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Heavy Cannabis Use Associated With Reduction in Activated and Inflammatory Immune Cell Frequencies in Antiretroviral Therapy–Treated Human Immunodeficiency Virus–Infected Individuals
Clinical Infectious Diseases ( IF 11.8 ) Pub Date : 2018-02-17 , DOI: 10.1093/cid/cix1116
Jennifer A Manuzak _{1,

2} , Toni M Gott _{1,

2} , Jay S Kirkwood ₁ , Ernesto Coronado _{1,

2} , Tiffany Hensley-McBain _{1,

2} , Charlene Miller _{1,

2} , Ryan K Cheu _{1,

2} , Ann C Collier ₃ , Nicholas T Funderburg ₄ , Jeffery N Martin ₅ , Michael C Wu ₆ , Nina Isoherranen ₁ , Peter W Hunt ₇ , Nichole R Klatt _{1,

2}

Affiliation

Cannabis is a widely used drug in the United States, and the frequency of cannabis use in the human immunodeficiency virus (HIV)–infected population is disproportionately high. Previous human and macaque studies suggest that cannabis may have an impact on plasma viral load; however, the relationship between cannabis use and HIV-associated systemic inflammation and immune activation has not been well defined.

中文翻译：

大量使用大麻与抗逆转录病毒治疗中活化和炎症免疫细胞频率的降低有关——治疗过的人类免疫缺陷病毒感染个体

大麻在美国是一种广泛使用的药物，在人类免疫缺陷病毒 (HIV) 感染人群中使用大麻的频率非常高。先前的人类和猕猴研究表明，大麻可能对血浆病毒载量产生影响；然而，大麻使用与 HIV 相关的全身炎症和免疫激活之间的关系尚未明确。

更新日期：2018-02-17

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