Bachground

Degree of saturation appears to have different effects on energy metabolism, which can help weight loss. The aim of study was to evaluate the influence of meals/dietary fats on energy metabolism of overweight subjects.

Methods

Systematic review and meta-analysis were conducted in the MEDLINE, Web of Science, Lilacs and Scopus database until January 2018 without language restriction. Randomized and controlled clinical trials with overweight adult subjects in whom evaluated diet or meal high PUFA, MUFA and SFA on energy metabolism was included. Study design, population, intervention and outcomes were abstracted from studies. Assessment for bias was conducted in identified trials. Data were analysed by difference between averages. Heterogeneity were performed and I² values greater than 50% showed heterogeneity.

Results

Energy expenditure (EE) did not change when compared MUFA and PUFA with CHO and SFA. Based on the meta-analysis, there is no scientific evidence demonstrating that unsaturated fatty acids (UFA) present favourable metabolic response in overweight individuals. Lipid, regardless of the presence of unsaturation is a macronutrient that provides a lower EE compared to CHO.

Conclusion

Scientific evidence did not sustain that unsaturated fats present favorable metabolic response in overweight subjects.

中文翻译：

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超重受试者中不饱和脂肪酸的代谢反应不好：荟萃分析的结果

Bachground

饱和度似乎对能量代谢有不同的影响，可以帮助减肥。研究的目的是评估膳食/饮食脂肪对超重受试者能量代谢的影响。

方法

在MEDLINE，Web of Science，Lilacs和Scopus数据库中进行了系统的审查和荟萃分析，直到2018年1月为止，并且没有语言限制。包括对体重超重的成人受试者进行的随机和对照临床试验，其中对饮食或膳食中高PUFA，MUFA和SFA进行了能量代谢评估。研究设计，人群，干预措施和结果从研究中抽象出来。在确定的试验中进行偏倚评估。通过平均值之间的差异分析数据。进行了异质性分析，I ²值大于50％则显示出异质性。

结果

将MUFA和PUFA与CHO和SFA进行比较时，能源支出（EE）不变。基于荟萃分析，没有科学证据表明不饱和脂肪酸（UFA）在超重个体中表现出有利的代谢反应。脂质，无论是否存在不饱和，都是一种丰富的营养素，与CHO相比，其EE较低。

结论

科学证据不能支持不饱和脂肪在超重受试者中表现出有利的代谢反应。