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Low-dose versus standard-dose azithromycin for treatment of yaws
The Lancet Global Health ( IF 19.9 ) Pub Date : 2018-02-15 , DOI: 10.1016/s2214-109x(18)30067-6
Lenka Mikalová , David Šmajs

In their Article in The Lancet Global Health, Michael Marks and colleagues1 compare the efficacy of low-dose azithromycin (20 mg/kg) versus standard-dose azithromycin (30 mg/kg) for the treatment of yaws. The lower dose of azithromycin is commonly used for trachoma elimination and, since yaws and trachoma are co-endemic in several regions,2 mass treatment with low-dose azithromycin could also aid yaws eradication. If a low-dose azithromycin treatment is as effective against yaws as standard-dose azithromycin, yaws eradication programmes can expect a considerable cost saving.

中文翻译:

低剂量与标准剂量阿奇霉素治疗偏航

Michael Marks及其同事在《柳叶刀全球健康》The Lancet Global Health)一文中比较了低剂量阿奇霉素(20 mg / kg)与标准剂量阿奇霉素(30 mg / kg)治疗偏航的功效。较低剂量的阿奇霉素通常用于消除沙眼,并且由于偏航和沙眼在几个地区是共同流行的,因此低剂量阿奇霉素的2种大规模治疗也可以帮助根除偏航。如果低剂量阿奇霉素治疗对偏航的效果与标准剂量阿奇霉素一样,则根除偏航计划可望节省大量成本。
更新日期:2018-03-10
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