当前位置：
X-MOL 学术
›
ACS Biomater. Sci. Eng.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Regulating Degradation Behavior by Incorporating Mesoporous Silica for Mg Bone Implants
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2018-02-15 00:00:00 , DOI: 10.1021/acsbiomaterials.8b00020 Youwen Yang 1, 2 , Xiaoning Guo 3 , Chongxian He 2 , Chengde Gao 2 , Cijun Shuai 1, 2, 4
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2018-02-15 00:00:00 , DOI: 10.1021/acsbiomaterials.8b00020 Youwen Yang 1, 2 , Xiaoning Guo 3 , Chongxian He 2 , Chengde Gao 2 , Cijun Shuai 1, 2, 4
Affiliation
|
Magnesium (Mg) alloys are potential bone implant materials because of their natural biodegradability, good biocompatibility and suitable mechanical properties. However, the too rapid degradation in physiological environment has delayed their introduction for orthopedic applications to date. To improve the degradation behavior, mesoporous silica (MS) was incorporated into ZK60 (Mg-6Zn-0.5Zr, wt %) via selective laser melting technology. Results showed that MS homogeneously incorporated in Mg matrix with good bonding interface. MS was chemical inert against Mg and shifted the corrosion potential positively, indicating an enhanced corrosion resistance. Moreover, MS promoted the deposition of apatite on surface and formed a compact protection layer, thus effectively preventing the further corrosion of Mg matrix. As a result, the degradation rate was reduced by 57%, with MS containing up to 8 wt %. In addition, ZK60/8MS composite exhibited improved biocompatibility. It was suggested the ZK60/8MS composite with improved degradation behavior and good biocompatibility was a potential candidate biomaterial for the bone implants.
中文翻译：
通过掺入介孔二氧化硅来调节镁骨植入物的降解行为
镁（Mg）合金由于其天然的生物降解性，良好的生物相容性和合适的机械性能而成为潜在的骨植入材料。然而，迄今为止，生理环境中的过快降解已经延迟了其在整形外科中的应用。为了改善降解行为，通过选择性激光熔融技术将中孔二氧化硅（MS）掺入ZK60（Mg-6Zn-0.5Zr，wt％）中。结果表明，MS均匀地结合在Mg基体中，具有良好的键合界面。MS对Mg呈化学惰性，正腐蚀电位正移，表明增强的耐腐蚀性。此外，MS促进了磷灰石在表面上的沉积并形成了致密的保护层，从而有效地防止了Mg基质的进一步腐蚀。因此，MS含量高达8 wt％，降解率降低了57％。另外，ZK60 / 8MS复合材料表现出改善的生物相容性。有人提出具有改善的降解行为和良好的生物相容性的ZK60 / 8MS复合材料是骨植入物的潜在候选生物材料。
更新日期：2018-02-15
中文翻译：
通过掺入介孔二氧化硅来调节镁骨植入物的降解行为
镁（Mg）合金由于其天然的生物降解性，良好的生物相容性和合适的机械性能而成为潜在的骨植入材料。然而，迄今为止，生理环境中的过快降解已经延迟了其在整形外科中的应用。为了改善降解行为，通过选择性激光熔融技术将中孔二氧化硅（MS）掺入ZK60（Mg-6Zn-0.5Zr，wt％）中。结果表明，MS均匀地结合在Mg基体中，具有良好的键合界面。MS对Mg呈化学惰性，正腐蚀电位正移，表明增强的耐腐蚀性。此外，MS促进了磷灰石在表面上的沉积并形成了致密的保护层，从而有效地防止了Mg基质的进一步腐蚀。因此，MS含量高达8 wt％，降解率降低了57％。另外，ZK60 / 8MS复合材料表现出改善的生物相容性。有人提出具有改善的降解行为和良好的生物相容性的ZK60 / 8MS复合材料是骨植入物的潜在候选生物材料。
京公网安备 11010802027423号