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Effects of Rifampin and Doxycycline Treatments in Patients With Uncomplicated Scrub Typhus: An Open-Label, Randomized, Controlled Trial
Clinical Infectious Diseases ( IF 8.2 ) Pub Date : 2018-02-15 , DOI: 10.1093/cid/ciy130
Yun Sung Kim 1 , Dong-Min Kim 1 , Na-Ra Yoon 1 , Mi-Sun Jang 1 , Choon-Mee Kim 2
Affiliation  

Doxycycline is currently the most frequently used treatment in patients with scrub typhus. However, doxycycline-resistant strains have been found, necessitating the development of a new treatment. Rifampin is known to be effective even for such strains. Our aim in this study was to compare the effects of rifampin and doxycycline treatment in patients with scrub typhus in areas in which resistance to doxycycline has not been reported.

中文翻译:

利福平和强力霉素治疗对单纯性斑疹伤寒患者的影响:开放标签,随机对照试验

强力霉素是目前治疗斑疹伤寒患者最常用的治疗方法。但是,已经发现了对多西环素具有抗性的菌株,因此有必要开发一种新的治疗方法。已知利福平即使对于此类菌株也有效。我们在这项研究中的目的是在尚未报告对多西环素有抗药性的地区,对利福平和多西环素治疗对斑疹伤寒患者的效果进行比较。
更新日期:2018-02-15
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