Two-Phase Flow in Liquid Chromatography, Part 2: Modeling,Industrial & Engineering Chemistry Research

当前位置： X-MOL 学术 › Ind. Eng. Chem. Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Two-Phase Flow in Liquid Chromatography, Part 2: Modeling
Industrial & Engineering Chemistry Research ( IF 3.8 ) Pub Date : 2018-02-22 00:00:00 , DOI: 10.1021/acs.iecr.7b05154
Franziska Ortner ₁ , Marco Mazzotti ₁

Affiliation

This contribution presents the derivation and solution of model equations for a chromatographic system in the presence of multiple fluid phases. While chromatographic models commonly account for adsorption and one single convective phase, macroscopic models for applications in natural reservoirs deal with multiphase flow but usually neglect adsorption effects. This work considers an equilibrium theory model and a lumped kinetic model which account for both multiphase flow and adsorption phenomena. Analytical and numerical solutions of these models are derived and applied to a specific chromatographic system, which was investigated in detail in a companion paper. The analysis of equilibrium theory solutions provides a deep insight in the mathematical and physical implications of two-phase flow and adsorption. The comparison of analytical and numerical solutions validates both models and highlights advantages and drawbacks. The presented model equations and solutions are of considerable interest not only in the context of liquid chromatography but also for several applications involving natural reservoirs.

中文翻译：

液相色谱中的两相流，第2部分：建模

这一贡献提出了在存在多个流体相的情况下色谱系统的模型方程式的推导和解。色谱模型通常考虑吸附和一个对流相，而在天然油藏中使用的宏观模型处理多相流，但通常忽略了吸附作用。这项工作考虑了一个平衡理论模型和集总动力学模型，该模型同时考虑了多相流和吸附现象。推导了这些模型的分析和数值解决方案，并将其应用于特定的色谱系统，并在随附的论文中进行了详细研究。平衡理论解的分析为两相流和吸附的数学和物理含义提供了深刻的见解。分析解决方案和数值解决方案的比较验证了这两种模型，并强调了优点和缺点。所提出的模型方程式和解不仅在液相色谱法中而且在涉及天然油藏的几种应用中都引起了极大的兴趣。

更新日期：2018-02-23

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11