Abstract Biomarkers (e.g. cytokines) that are commonly measured to assess the immunomodulatory effects of nano- or micro-particulates may be adsorbed on their surfaces and/or absorbed within internal regions, thereby, generating an inaccurately low measure of immunotoxic effect. We provide this commentary, therefore, as a cautionary recommendation that previously published data be reassessed, and future investigations consider potential artifacts and data misinterpretation carefully.

中文翻译：

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纳米材料免疫毒性的重新评估

摘要 通常用于评估纳米或微米颗粒免疫调节作用的生物标志物（例如细胞因子）可能被吸附在其表面和/或被吸收在内部区域内，从而产生免疫毒性作用的不准确的低测量。因此，我们提供此评论作为警示性建议，即重新评估先前发布的数据，并在未来的调查中仔细考虑潜在的伪影和数据误解。