Legionella pneumophila secretes over 300 effector proteins that manipulate host cells. This multiplicity of effectors hampers the characterization of their individual roles. Shames et al. report a new approach to solve the enigma of Legionella effector function by using INSeq to analyse effector functions in the context of infection.

中文翻译：

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INSeq探索军团菌效应器：新的功能性见解

嗜肺军团杆菌分泌300多种操纵宿主细胞的效应蛋白。效应子的多样性妨碍了其各自角色的表征。Shames等。报告了一种新方法，通过使用INSeq在感染的情况下分析效应子功能来解决军团菌效应子功能的谜团。