The rice blast fungus, Magnaporthe oryzae, causes one of the most destructive diseases of cultivated rice in the world. Infections caused by this recalcitrant pathogen lead to the annual destruction of approximately 10–30% of the rice harvested globally. The fungus undergoes extensive developmental changes to be able to break into plant cells, build elaborate infection structures, and proliferate inside host cells without causing visible disease symptoms. From a molecular standpoint, we are still in the infancy of understanding how M. oryzae manipulates the host during this complex multifaceted infection. Here, we describe recent advances in our understanding of the cell biology of M. oryzae biotrophic interaction and key molecular factors required for the disease establishment in rice cells.

稻瘟病菌Magnaporthe oryzae引起世界上栽培稻破坏性最强的疾病之一。由这种顽固性病原体引起的感染导致每年全球水稻收成的大约10％至30％被破坏。真菌经历了广泛的发育变化，能够进入植物细胞，建立精致的感染结构，并在宿主细胞内增殖而不会引起明显的疾病症状。从分子角度看，我们仍处于了解这种复杂的多面感染过程中米曲霉如何操纵宿主的初期阶段。在这里，我们描述了我们对米曲霉细胞生物学的理解的最新进展。 水稻细胞中疾病建立所需的生物营养相互作用和关键分子因素。