With the pipeline of new antibiotics running dry, vaccines are being proposed as a key part of the toolkit used to fight antimicrobial resistance.¹ Amy Ginsburg and Keith Klugman (November 2017, e1176–77)² suggest that a reduction in resistant pathogens might be easier to achieve in many countries via vaccines than through other interventions, such as improved hygiene and sanitation. However, vaccines are rarely designed to target resistant pathogens directly, with the notable exception of pneumococcal conjugate vaccines (PCVs) that protect against serotypes of Streptococcus pneumoniae displaying high resistance frequency.

中文翻译：

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接种疫苗以降低抗药性

随着越来越多的新抗生素逐渐枯竭，人们正在提议将疫苗作为抗药性抗药性工具包的关键部分。¹艾米·金斯堡（Amy Ginsburg）和基思·克鲁格曼（Keith Klugman）（2017年11月，e1176–77）²表明，在许多国家，通过疫苗减少耐药病原体可能比通过其他干预措施（如改善卫生和卫生条件）更容易实现。但是，疫苗很少直接针对耐药病原体而设计，值得注意的是肺炎球菌结合疫苗（PCV）可以抵抗表现出高耐药频率的肺炎链球菌血清型。