An undergraduate experiment for the organic laboratory is described that utilizes microwave heating to prepare 5-substituted 1H-tetrazole derivatives through a (3 + 2) cycloaddition between aryl nitriles and sodium azide. The reaction mixture is analyzed by thin layer chromatography. The products are purified through an acid–base extraction and recrystallization. Characterization is accomplished using melting point, infrared, ¹H NMR, and ¹³C NMR spectroscopy. Students are tasked with determining and confirming the structure of their product based on their assigned nitrile and characterization data.

中文翻译：

---

本科生有机实验：水溶液中微波加热（3 + 2）环加成反应生成四唑

描述了有机实验室的一个本科生实验，该实验利用微波加热通过芳基腈和叠氮化钠之间的（3 + 2）环加成反应来制备5位取代的1 H-四唑衍生物。通过薄层色谱法分析反应混合物。产品通过酸碱萃取和重结晶纯化。使用熔点，红外，¹ H NMR和¹³ C NMR光谱进行表征。学生的任务是根据分配的腈和特征数据确定和确认产品的结构。