Discovery of a Short‐Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid,ChemBioChem

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Discovery of a Short‐Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid
ChemBioChem ( IF 2.6 ) Pub Date : 2018-03-22 , DOI: 10.1002/cbic.201700621
Anna K Stavrinides _{1,

2} , Evangelos C Tatsis ₁ , Thu-Thuy Dang ₁ , Lorenzo Caputi ₁ , Clare E M Stevenson ₁ , David M Lawson ₁ , Bernd Schneider ₃ , Sarah E O'Connor ₁

Affiliation

Cryptic and unnatural natural products: A short‐chain alcohol dehydrogenase from plant producers of monoterpene indole alkaloids (C. roseus and R. serpentina) reduces strictosidine aglycone to form an alkaloid that does not correspond to any previously reported compound.