Three new bisabolane sesquiterpenoid esters, aspertenols A-B (1-3), and six known compounds (4-9) were isolated from the fungus Aspergillus tennesseensis. The structures of new compounds were elucidated by extensive spectroscopic analysis. The cytotoxicities of 1-9 against A549, K562, and ASPC cell lines were tested by using the CCK8 method. Compounds 1, 3, 4, 6, 7, and 9 showed inhibition on K562 cell line with IC₅₀ values in the range from 16.6 to 72.7 μM. Compounds 1, 4, and 9 showed moderate inhibitory activity against A549 with IC₅₀ of 43.5, 70.2, and 61.1 μM, respectively.

中文翻译：

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田纳曲霉新的具有细胞毒性的酚双水杨醚倍半萜衍生物。

从真菌Asnessgillus tennesseensis中分离出了三种新的双倍半硼烷倍半萜酸酯，曲霉酚AB（1-3）和六种已知化合物（4-9）。通过广泛的光谱分析阐明了新化合物的结构。通过使用CCK8方法测试了1-9对A549，K562和ASPC细胞系的细胞毒性。化合物1、3、4、6、7和9对K562细胞系表现出抑制作用，IC ₅₀值为16.6至72.7μM。化合物1、4和9对A549表现出中等抑制活性，IC _50分别为43.5、70.2和61.1μM。