One of the major challenges faced by the biomedical industry is the development of robust synthetic surfaces that can resist bacterial colonization. Much inspiration has been drawn recently from naturally occurring mechano-bactericidal surfaces such as the wings of cicada (Psaltoda claripennis) and dragonfly (Diplacodes bipunctata) species in fabricating their synthetic analogs. However, the bactericidal activity of nanostructured surfaces is observed in a particular range of parameters reflecting the geometry of nanostructures and surface wettability. Here, several of the nanometer-scale characteristics of black silicon (bSi) surfaces including the density and height of the nanopillars that have the potential to influence the bactericidal efficiency of these nanostructured surfaces have been investigated. The results provide important evidence that minor variations in the nanoarchitecture of substrata can substantially alter their performance as bactericidal surfaces.

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生物医学工业面临的主要挑战之一是开发出能够抵抗细菌定植的坚固的合成表面。最近从自然发生的机械杀菌表面（如蝉翼（Psaltoda claripennis）和蜻蜓（Diplacodes bipunctata））来制造其合成类似物。然而，在反映纳米结构的几何形状和表面润湿性的特定参数范围内观察到纳米结构表面的杀菌活性。在这里，已经研究了黑硅（bSi）表面的几个纳米尺度特征，包括可能影响这些纳米结构表面杀菌效率的纳米柱的密度和高度。结果提供了重要的证据，表明底层纳米结构的微小变化会大大改变其作为杀菌表面的性能。

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