Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful. Diets high in fructose can rapidly produce all of the key features of the metabolic syndrome. Here we review the biology of fructose metabolism as well as potential mechanisms by which excessive fructose consumption may contribute to cardiometabolic disease.

中文翻译：

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果糖代谢与代谢性疾病

越来越多的食糖消费被认为是导致肥胖和糖尿病及其相关的心脏代谢风险的全球流行病的原因。由于其独特的代谢特性，糖中的果糖成分可能特别有害。果糖含量高的饮食可以迅速产生新陈代谢综合症的所有关键特征。在这里，我们审查了果糖代谢的生物学以及果糖消耗过多可能导致心脏代谢疾病的潜在机制。