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Robust Ionic Current Sensor for Bacterial Cell Size Detection
ACS Sensors ( IF 8.2 ) Pub Date : 2018-02-08 00:00:00 , DOI: 10.1021/acssensors.8b00045
Hirotoshi Yasaki , Taisuke Shimada , Takao Yasui 1 , Takeshi Yanagida 2, 3 , Noritada Kaji 1 , Masaki Kanai 2 , Kazuki Nagashima 2 , Tomoji Kawai 3 , Yoshinobu Baba 4
Affiliation  

Ionic current sensing methods are useful tools for detecting sub- to several-micron scale particles such as bacteria. However, conventional commercially available ionic current sensing devices are not suitable for on-site measurement use because of inherent limitations on their robustness. Here, we proposed a portable robust ionic current sensor (Robust-ICS) using a bridge circuit that offers a high signal-to-noise (S/N) ratio by suppressing background current. Because the Robust-ICS can tolerate increased noise in current sensing, a simple, lightweight electromagnetic shield can be used and measurements under large electromagnetic noise conditions can be made. The weight of the device was lowered below 4 kg and outdoor particle detection measurements were completed successfully. Accuracy of size detection of Staphylococcus aureus (S. aureus) was equivalent to that obtained by SEM imaging.

中文翻译:

用于细菌细胞大小检测的强大离子电流传感器

离子电流感测方法是检测亚微米级至几微米级颗粒(例如细菌)的有用工具。然而,由于其坚固性的固有局限性,常规的市售离子电流感测装置不适合现场测量使用。在这里,我们提出了一种使用桥式电路的便携式鲁棒离子电流传感器(Robust-ICS),该桥式电路通过抑制背景电流来提供高信噪比(S / N)。由于Robust-ICS可以容忍电流感测中增加的噪声,因此可以使用简单,轻巧的电磁屏蔽,并且可以在较大的电磁噪声条件下进行测量。该设备的重量降至4 kg以下,并成功完成了室外颗粒物检测。尺寸检测精度金黄色葡萄球菌S. aureus)相当于通过SEM成像获得的金黄色葡萄球菌
更新日期:2018-02-08
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