Short‐chain fatty acid sodium butyrate (NaB) is the byproduct of bacterial anaerobic fermentation of dietary fiber in the colon, and has been shown to have an antitumor effect on colorectal cancer (CRC). The miR‐200 family is a key regulator of the epithelial‐mesenchymal transition (EMT). We investigate the role of miR‐200s expression on cell migration in NaB‐treated CRC cells.

中文翻译：

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丁酸钠通过增强miR-200c表达下调Bmi-1抑制大肠癌细胞迁移

短链脂肪酸丁酸钠（NaB）是结肠中膳食纤维细菌厌氧发酵的副产物，并已显示对结肠直肠癌（CRC）具有抗肿瘤作用。miR-200家族是上皮-间质转化（EMT）的关键调节剂。我们研究了NaB处理的CRC细胞中miR-200s表达在细胞迁移中的作用。