Obstructive sleep apnoea (OSA) is very common with a growing prevalence over the past two decades that at least partly reflects the rising prevalence of obesity.¹ OSA is traditionally diagnosed on the basis of frequency of sleep-disordered breathing events measured during overnight polysomnography, but this approach is poorly suited to the clinical evaluation of large at-risk populations. In addition, a large prospective randomised trial² cast doubt on previous evidence supporting beneficial effects of continuous positive airway pressure (CPAP) on cardiovascular outcomes.

中文翻译：

---

阻塞性睡眠呼吸暂停的挑战

阻塞性睡眠呼吸暂停（OSA）非常常见，在过去的20年中患病率呈上升趋势，这至少部分反映了肥胖症患病率的上升。¹ OSA传统上是根据通宵多导睡眠图测得的睡眠呼吸障碍频率来诊断的，但这种方法不适合大型危险人群的临床评估。此外，一项大型的前瞻性随机试验²怀疑先前证据支持持续气道正压通气（CPAP）对心血管结局的有益作用。