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l‐Menthol‐Assisted Synthesis of P‐Stereogenic Phosphinous Acid Amides and Phosphine‐Boranes
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2018-04-10 , DOI: 10.1002/ejoc.201800065
Adam Włodarczyk 1 , Anna E. Kozioł 2 , Marek Stankevič 1
Affiliation  

l‐Menthol was used as a chiral auxiliary for the efficient and simple synthesis of a diastereomerically pure phosphonous acid‐borane monoester monoamide. This compound was used for the synthesis of various enantiomerically enriched phosphinous acid‐borane amides and secondary or tertiary phosphine‐boranes. The latter were obtained through a sequential reductive‐cleavage/alkylation process.
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中文翻译:

l-薄荷醇辅助合成对-立体异构亚膦酰胺和膦-硼烷

l薄荷醇被用作手性助剂,用于高效,简单地合成非对映体纯亚膦酸硼烷单酯单酰胺。该化合物用于合成各种对映体富集的次膦酸-硼烷酰胺和仲或叔膦-硼烷。后者是通过顺序还原-裂解/烷基化过程获得的。
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更新日期:2018-04-10
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