Black phosphorus nanosheets for rapid microRNA detection†,Nanoscale

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Black phosphorus nanosheets for rapid microRNA detection†
Nanoscale ( IF 6.7 ) Pub Date : 2018-02-07 00:00:00 , DOI: 10.1039/c7nr08900g
Jie Zhou _{1,

2,

3,

4,

5} , Zhongjun Li _{3,

4,

6,

7,

8} , Ming Ying _{3,

4,

5,

9,

10} , Maixian Liu _{1,

2,

3,

4,

5} , Xiaomei Wang _{4,

5,

11,

12,

13} , Xianyou Wang _{3,

4,

5,

14} , Liwei Cao _{3,

4,

5,

14} , Han Zhang _{3,

4,

6,

7,

8} , Gaixia Xu _{1,

2,

3,

4,

5}

Affiliation

Key Laboratory of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province
College of Optoelectronic Engineering
Shenzhen University
Shenzhen 518060
China
Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics
SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology
and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province
College of Life Sciences
Shenzhen Key Laboratory of Marine Bioresources and Ecology/Shen Zhen Key Laboratory of Microbial Genetic Engineering
Department of Physiology
School of Basic Medical Sciences
Shenzhen University Health Sciences Center
Nanophotonics Research Centre

Herein, for the first time, a sensitive sensing platform for rapid detection of microRNA was developed by employing black phosphorus nanosheets as the fluorescence quenching material. The biosensor displayed a good linear response to microRNA ranging from 10 nM to 1000 nM. Moreover, the biosensor could distinguish triple nucleotide polymorphism.

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