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Associations Between Serum Bone Biomarkers in Early Breast Cancer and Development of Bone Metastasis: Results From the AZURE (BIG01/04) Trial
Journal of the National Cancer Institute ( IF 9.9 ) Pub Date : 2018-02-07 , DOI: 10.1093/jnci/djx280
Janet Brown 1, 2 , Emma Rathbone 1, 2, 3 , Samantha Hinsley 4 , Walter Gregory 4 , Fatma Gossiel 5 , Helen Marshall 4 , Roger Burkinshaw 1 , Helen Shulver 1 , Hasina Thandar 6 , Gianfilippo Bertelli 7 , Keane Maccon 8 , Angela Bowman 9 , Andrew Hanby 2 , Richard Bell 10 , David Cameron 9 , Robert Coleman 1
Affiliation  

Adjuvant therapies can prevent/delay bone metastasis development in breast cancer. We investigated whether serum bone turnover markers in early disease have clinical utility in identifying patients with a high risk of developing bone metastasis.

中文翻译:

早期乳腺癌血清骨生物标志物与骨转移发展之间的关联:AZURE (BIG01/04) 试验的结果

辅助疗法可以预防/延缓乳腺癌骨转移的发展。我们研究了早期疾病中的血清骨转换标志物是否在识别具有高发生骨转移风险的患者方面具有临床效用。
更新日期:2018-08-13
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