Benzylic chlorides were treated with N‐methylmorpholine N‐oxide (NMO) and then NH₂OH·HCl and potassium carbonate followed by the addition of Oxone® in the presence of acetylene derivatives to give the corresponding 3‐arylisoxazole‐4,5‐dicarboxylates in good to moderate yields. This one‐pot transformation used readily available materials and was performed under transition‐metal‐free conditions.

中文翻译：

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从苄基氯化物和乙炔二羧酸盐一锅法制备3-Arylisoxazole-4,5-二羧酸盐

先用N-甲基吗啉N-氧化物（NMO），然后用NH ₂ OH · HCl和碳酸钾处理苯甲酰氯，然后在乙炔衍生物存在下加入Oxone®，得到相应的3-芳基异恶唑-4,5-二羧酸酯中等至中等的产量。这种一锅法改造使用了现成的材料，并在无过渡金属的条件下进行。