Hormone therapy (HT) was widely prescribed in the 1980s and 1990s and has been controversial since the initial results of the Women's Health Initiative (WHI) trial in the early 2000s suggested that it increased risk for breast cancer and coronary heart disease and did not prolong life. However, more recent data and reexamination of the WHI results suggest that HT is safe and effective for many women when used around the time of menopause. Two experts debate the 2017 Hormone Therapy Position Statement of The North American Menopause Society, which recommends HT as first-line treatment of vasomotor symptoms, and apply it to the care of Ms. R, a 52-year-old woman with severe hot flashes, sleep disturbance, and irritability.

激素疗法（HT）在1980年代和1990年代被广泛开出处方，并且自2000年代初期妇女健康倡议（WHI）试验的初步结果表明，激素疗法（HT）增加了患乳腺癌和冠心病的风险以来，并没有持续很长时间，因此一直引起争议。生活。但是，最新的数据和对WHI结果的重新检验表明，在绝经前后使用HT对许多妇女而言是安全有效的。两位专家对北美更年期协会2017年激素治疗立场声明进行辩论，该声明建议将HT作为血管舒缩症状的一线治疗方法，并将其应用于52岁患有严重潮热妇女的R女士的护理中，睡眠障碍和烦躁不安。