A unique coupled redox organocatalysis system using flavin and iodine catalysts efficiently promoted the metal-free aerobic oxidative direct sulfenylation of indoles with thiols at ambient temperature without any sacrificial reagents, except environmentally benign molecular oxygen. Biomimetic flavin catalysis plays multiple roles in aerobic oxidative transformations, not only regenerating I₂ from in situ generated I⁻, but also converting thiols into disulfides.

中文翻译：

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黄素-碘偶联有机催化在温和条件下用硫醇对吲哚进行需氧氧化直接亚磺酰基化

使用黄素和碘催化剂的独特偶联氧化还原有机催化系统可在环境温度下有效地促进吲哚类化合物与金属的无金属有氧氧化直接亚磺酰化反应，而无需使用任何牺牲试剂，除了对环境有益的分子氧。仿生催化黄素起着有氧氧化转换多个角色，不仅再生我₂从原位生成的I ^- ，也将硫醇成二硫化物。