Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes,International Journal of Epidemiology

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Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes
International Journal of Epidemiology ( IF 7.7 ) Pub Date : 2018-02-05 , DOI: 10.1093/ije/dyx266
Maria C Magnus _{1,

2,

3} , Sjurdur F Olsen ₄ , Charlotta Granstrom ₄ , Nicolai A Lund-Blix _{1,

5} , Jannet Svensson ₆ , Jesper Johannesen ₆ , Abigail Fraser _{2,

3,

7} , Torild Skrivarhaug ₅ , Geir Joner _{5,

8} , Pål R Njølstad _{9,

10} , Ketil Størdal _{1,

11} , Lars C Stene ₁

Affiliation

Division for Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway.
MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK.
Department of Population Health Sciences, Bristol Medical School, Bristol, UK.
Centre for Fetal Programming, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Department of Pediatrics, Oslo University Hospital, Oslo, Norway.
Department of Pediatrics, Copenhagen University Hospital, Herlev, Denmark.
NIHR Bristol Biomedical Research Centre at the University Hospitals Bristol, NHS Foundation Trust and the University of Bristol, Bristol, UK.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.
Department of Pediatrics, Ostfold Hospital Trust, Fredrikstad, Norway.

Our objective was to examine the associations of parental body mass index (BMI) and maternal gestational weight gain with childhood-onset type 1 diabetes. Comparing the associations of maternal and paternal BMI with type 1 diabetes in the offspring will provide further insight into the role of unmeasured confounding by characteristics linked to BMI in both parents.

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