Theoretically, a variety of mechanisms can make amphimixis advantageous due to reshuffling of offspring genotypes. Recently, it has been shown experimentally that some of these mechanisms can indeed work in artificial populations. However, we still do not know which of them, if any, are relevant in nature, and the available indirect estimates seem to suggest that neither negative nor positive selection in natural populations is strong enough to provide evolutionary protection for obligate amphimixis. Thus, progress in understanding the evolution of amphimixis will depend on direct measurements of the strength of natural selection.

中文翻译：

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通过性，大自然在告诉我们一些重要的事情

从理论上讲，由于后代基因型的改组，各种机制都可以使两栖动物具有优势。最近，实验证明这些机制中的某些机制确实可以在人工种群中起作用。但是，我们仍然不知道它们中的哪一个（如果有的话）本质上是相关的，并且可用的间接估计似乎表明，自然种群中的阴性或阳性选择都没有足够强到可以为专性两栖动物提供进化保护。因此，了解两栖类动物进化的进展将取决于对自然选择强度的直接测量。