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Loganic Acid Methyltransferase: Insights into the Specificity of Methylation on an Iridoid Glycoside
ChemBioChem ( IF 3.2 ) Pub Date : 2018-03-08 , DOI: 10.1002/cbic.201700679 Nektaria Petronikolou 1, 2 , Allison J. Hollatz 3 , Mary A. Schuler 1, 4 , Satish K. Nair 1, 2, 5
ChemBioChem ( IF 3.2 ) Pub Date : 2018-03-08 , DOI: 10.1002/cbic.201700679 Nektaria Petronikolou 1, 2 , Allison J. Hollatz 3 , Mary A. Schuler 1, 4 , Satish K. Nair 1, 2, 5
Affiliation
Reading the crystal ball: The crystal structure of loganic acid O‐methyltransferase from Catharanthus roseus (CrLAMT) revealed how the enzyme has evolved for methylation of a large glycosylated substrate. It also shed light on the molecular basis for the enzyme's high specificity towards a glycosylated and hydroxylated iridoid ring.
中文翻译:
Loganic酸甲基转移酶:洞悉类环烷苷糖苷甲基化的特异性。
阅读晶体球:长春花(CaLAranthus roseus)的对数酸O-甲基转移酶(CrLAMT)的晶体结构揭示了该酶如何进化为大型糖基化底物的甲基化。它也从分子学的角度揭示了该酶对糖基化和羟基化的环烯醚环的高度特异性。
更新日期:2018-03-08
中文翻译:
Loganic酸甲基转移酶:洞悉类环烷苷糖苷甲基化的特异性。
阅读晶体球:长春花(CaLAranthus roseus)的对数酸O-甲基转移酶(CrLAMT)的晶体结构揭示了该酶如何进化为大型糖基化底物的甲基化。它也从分子学的角度揭示了该酶对糖基化和羟基化的环烯醚环的高度特异性。