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Lipid nano scale cargos for the protection and delivery of food bioactive ingredients and nutraceuticals
Trends in Food Science & Technology ( IF 15.3 ) Pub Date : 2018-02-03 , DOI: 10.1016/j.tifs.2018.02.001
Sahar Akhavan , Elham Assadpour , Iman Katouzian , Seid Mahdi Jafari

Background

The encapsulation and liberation technologies for bioactive food ingredients has opened the door to innovative and significant applications in food, nutrition, and pharmaceutical fields via the employment of nanotechnology. Coating materials in the formulation of nanocapsules are mostly lipid, carbohydrate or protein-based. The nanoencapsulation procedure in the food and nutraceutical areas involves the incorporation of natural ingredients, such as volatile additives, polyphenols, aromas, colors, vitamins, enzymes, oils and antimicrobial compounds in nano-sized capsules, providing the opportunities for higher stability and retention for the sensitive molecules against decomposition and loss of nutritional value during the production process or delivery along with offering a sustained release.

Scope and approach

This review highlights the most recent nanoencapsulation advancements along with the formulations mainly based on lipid components; i.e., nanoemulsions, nanoliposomes and nanostructured lipid carriers in terms of preparation strategies, their classes, composition, attributes, analysis techniques, worked examples, and implementation in functional foods along with their upcoming evolution and future trends.

Key findings and conclusions

Nanocapsules with lipid formulations are possible alternatives to micro-sized carriers owing to the enormous surface area and the following features which they offer, such as improved solubility, high bioavailability and establishment of sustained liberation of the nanoencapsulated food constituents and nutraceuticals.



中文翻译:

脂质纳米级货物,用于保护和运输食品生物活性成分和保健食品

背景

通过使用纳米技术,生物活性食品成分的封装和释放技术为食品,营养和制药领域的创新和重要应用打开了大门。纳米胶囊制剂中的包衣材料主要基于脂质,碳水化合物或蛋白质。食品和营养保健领域的纳米囊化程序涉及将天然成分(例如挥发性添加剂,多酚,香气,色素,维生素,酶,油和抗微生物化合物)掺入纳米大小的胶囊中,从而提供了更高的稳定性和保留性。敏感分子在生产过程或输送过程中不会分解和失去营养价值,并提供持续释放。

范围和方法

这篇综述着重介绍了最新的纳米封装技术以及主要基于脂质成分的制剂。即纳米乳剂,纳米脂质体和纳米结构脂质载体的制备策略,类别,组成,属性,分析技术,有效的例子以及在功能性食品中的应用以及它们的未来发展和未来趋势。

主要发现和结论

具有脂质制剂的纳米胶囊由于其巨大的表面积和它们提供的以下功能(例如,提高的溶解度,高的生物利用度以及建立了纳米囊封的食品成分和营养保健品的持久释放),因此可以替代微型载体。

更新日期:2018-02-03
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