Sleep is a biological enigma that has raised numerous questions about the inner workings of the brain. The fundamental question of why our nervous systems have evolved to require sleep remains a topic of ongoing scientific deliberation. This question is largely being addressed by research using animal models of sleep. Drosophila melanogaster, also known as the common fruit fly, exhibits a sleep state that shares common features with many other species. Drosophila sleep studies have unearthed an immense wealth of knowledge about the neuroscience of sleep. Given the breadth of findings published on Drosophila sleep, it is important to consider how all of this information might come together to generate a more holistic understanding of sleep. This review provides a comprehensive summary of the neurobiology of Drosophila sleep and explores the broader insights and implications of how sleep is regulated across species and why it is necessary for the brain.

睡眠是一个生物学谜团，引发了许多关于大脑内部运作的问题。为什么我们的神经系统进化到需要睡眠这个基本问题仍然是一个正在进行的科学审议的话题。这个问题主要通过使用睡眠动物模型的研究来解决。黑腹果蝇也称为普通果蝇，其睡眠状态与许多其他物种具有共同特征。果蝇睡眠研究挖掘出了有关睡眠神经科学的大量知识。鉴于已发表的关于果蝇睡眠的广泛研究结果，重要的是要考虑如何将所有这些信息结合在一起以产生对睡眠的更全面的理解。这篇综述对果蝇睡眠的神经生物学进行了全面的总结，并探讨了睡眠如何在不同物种之间进行调节以及为什么它对大脑是必要的更广泛的见解和影响。