Benefaction of probiotics for human health: A review,Journal of Food and Drug Analysis

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Benefaction of probiotics for human health: A review
Journal of Food and Drug Analysis ( IF 2.6 ) Pub Date : 2018-07-01 , DOI: 10.1016/j.jfda.2018.01.002
Rout George Kerry ₁ , Jayanta Kumar Patra _{1,

2} , Sushanto Gouda ₃ , Yooheon Park ₂ , Han-Seung Shin ₄ , Gitishree Das ₂

Affiliation

Humans are a unique reservoir of heterogeneous and vivacious group of microbes, which together forms the human-microbiome superorganism. Human gut serves as a home to over 100-1000 microbial species, which primarily modulate the host internal environment and thereby, play a major role in host health. This spectacular symbiotic relationship has attracted extensive research in this field. More specifically, these organisms play key roles in defense function, eupepsia along with catabolism and anabolism, and impact brain-gut responses. The emergence of microbiota with resistance and tolerance to existing conventional drugs and antibiotics has decreased the drug efficacies. Furthermore, the modern biotechnology mediated nano-encapsulated multiplex supplements appear to be high cost and inconvenient. Henceforth, a simple, low-cost, receptive and intrinsic approach to achieve health benefits is vital in the present era. Supplementation with probiotics, prebiotics, and synbiotics has shown promising results against various enteric pathogens due to their unique ability to compete with pathogenic microbiota for adhesion sites, to alienate pathogens or to stimulate, modulate and regulate the host's immune response by initiating the activation of specific genes in and outside the host intestinal tract. Probiotics have also been shown to regulate fat storage and stimulate intestinal angiogenesis. Hence, this study aims to underline the possible beneficial impact of probiotics for human health and medical sectors and for better lifestyle.

中文翻译：

益生菌对人类健康的益处：综述

人类是一个独特的异质且活泼的微生物群，它们共同形成了人类-微生物组超有机体。人类肠道是超过 100-1000 种微生物的家园，它们主要调节宿主内部环境，从而在宿主健康中发挥重要作用。这种壮观的共生关系吸引了该领域的广泛研究。更具体地说，这些生物体在防御功能、分解代谢和合成代谢中发挥关键作用，并影响脑-肠反应。对现有常规药物和抗生素具有耐药性和耐受性的微生物群的出现降低了药物疗效。此外，现代生物技术介导的纳米封装复合补充剂似乎成本高且不方便。从此，一个简单，低成本，在当今时代，获得健康益处的接受性和内在方法至关重要。补充益生菌、益生元和合生元已显示出针对各种肠道病原体的有希望的结果，因为它们具有与病原微生物群竞争粘附位点、异化病原体或通过启动特定的激活来刺激、调节和调节宿主免疫反应的独特能力。宿主肠道内外的基因。益生菌也被证明可以调节脂肪储存和刺激肠道血管生成。因此，本研究旨在强调益生菌对人类健康和医疗部门以及改善生活方式可能产生的有益影响。合生元因其独特的能力与病原微生物群竞争粘附位点、异化病原体或通过启动宿主内外特定基因的激活来刺激、调节和调节宿主的免疫反应，已显示出对各种肠道病原体的有希望的结果肠道。益生菌也被证明可以调节脂肪储存和刺激肠道血管生成。因此，本研究旨在强调益生菌对人类健康和医疗部门以及改善生活方式可能产生的有益影响。合生元因其独特的能力与病原微生物群竞争粘附位点、异化病原体或通过启动宿主内外特定基因的激活来刺激、调节和调节宿主的免疫反应，已显示出对各种肠道病原体的有希望的结果肠道。益生菌也被证明可以调节脂肪储存和刺激肠道血管生成。因此，本研究旨在强调益生菌对人类健康和医疗部门以及改善生活方式可能产生的有益影响。通过启动宿主肠道内外特定基因的激活来产生免疫反应。益生菌也被证明可以调节脂肪储存和刺激肠道血管生成。因此，本研究旨在强调益生菌对人类健康和医疗部门以及改善生活方式可能产生的有益影响。通过启动宿主肠道内外特定基因的激活来产生免疫反应。益生菌也被证明可以调节脂肪储存和刺激肠道血管生成。因此，本研究旨在强调益生菌对人类健康和医疗部门以及改善生活方式可能产生的有益影响。

更新日期：2018-07-01

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