Squeezing Flux Out of Fat,Trends in Endocrinology & Metabolism

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Squeezing Flux Out of Fat
Trends in Endocrinology & Metabolism ( IF 11.4 ) Pub Date : 2018-04-01 , DOI: 10.1016/j.tem.2018.01.005
Alba Gonzalez-Franquesa ₁ , Mary-Elizabeth Patti ₂

Affiliation

Merging transcriptomics or metabolomics data remains insufficient for metabolic flux estimation. Ramirez et al. integrate a genome-scale metabolic model with extracellular flux data to predict and validate metabolic differences between white and brown adipose tissue. This method allows both metabolic phenotyping and the identification of potential therapeutic targets for obesity.

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