Preeclampsia is a serious pregnancy disorder characterized by the onset of high blood pressure and proteinuria. Although the understanding of the disease is increasing, it remains without treatment, other than the delivery of the baby and the placenta. This review sets out to discuss some new developments and strategies in the treatment of preeclampsia. We briefly review the current knowledge on the preeclamptic pathophysiology. We then examine the recent trends in preeclampsia treatment and, in particular, the tracks of potential therapeutic targets. Finally, we focus on the possibilities nanocarriers could offer in the management of preeclampsia. Indeed, nanocarriers could help to prevent transplacental passage and promote placental-specific drug delivery, thereby enhancing efficacy and improving safety. Tendencies are then drawn from the available studies on the optimal characteristics of a nanocarrier to deliver drugs to the placenta.

子痫前期是一种严重的妊娠疾病，其特征在于高血压和蛋白尿的发作。尽管对疾病的了解在增加，但除分娩婴儿和胎盘外，仍未接受任何治疗。本文旨在探讨先兆子痫的一些新发展和新策略。我们简要回顾了有关先兆子痫病理生理的最新知识。然后，我们检查了先兆子痫治疗的最新趋势，尤其是潜在治疗靶点的轨迹。最后，我们关注纳米载体在子痫前期治疗中可能提供的可能性。实际上，纳米载体可以帮助防止胎盘通过并促进胎盘特异性药物的输送，从而提高疗效并提高安全性。