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Advances in Carbon Nanotubes–Hydrogel Hybrids in Nanomedicine for Therapeutics
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2018-02-01 , DOI: 10.1002/adhm.201701213 Arti Vashist 1 , Ajeet Kaushik 1 , Atul Vashist 2 , Vidya Sagar 1 , Anujit Ghosal 3 , Y K Gupta 4 , Sharif Ahmad 5 , Madhavan Nair 1
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2018-02-01 , DOI: 10.1002/adhm.201701213 Arti Vashist 1 , Ajeet Kaushik 1 , Atul Vashist 2 , Vidya Sagar 1 , Anujit Ghosal 3 , Y K Gupta 4 , Sharif Ahmad 5 , Madhavan Nair 1
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In spite of significant advancement in hydrogel technology, low mechanical strength and lack of electrical conductivity have limited their next‐level biomedical applications for skeletal muscles, cardiac and neural cells. Host–guest chemistry based hybrid nanocomposites systems have gained attention as they completely overcome these pitfalls and generate bioscaffolds with tunable electrical and mechanical characteristics. In recent years, carbon nanotube (CNT)‐based hybrid hydrogels have emerged as innovative candidates with diverse applications in regenerative medicines, tissue engineering, drug delivery devices, implantable devices, biosensing, and biorobotics. This article is an attempt to recapitulate the advancement in synthesis and characterization of hybrid hydrogels and provide deep insights toward their functioning and success as biomedical devices. The improved comparative performance and biocompatibility of CNT–hydrogels hybrids systems developed for targeted biomedical applications are addressed here. Recent updates toward diverse applications and limitations of CNT hybrid hydrogels is the strength of the review. This will provide a holistic approach toward understanding of CNT‐based hydrogels and their applications in nanotheranostics.
中文翻译：
碳纳米管-水凝胶杂化物在纳米医学治疗中的进展
尽管水凝胶技术取得了显着进步，但机械强度低和缺乏导电性限制了其在骨骼肌、心脏和神经细胞的下一级生物医学应用。基于主客体化学的杂化纳米复合材料系统引起了人们的关注，因为它们完全克服了这些缺陷并产生具有可调节电气和机械特性的生物支架。近年来，基于碳纳米管（CNT）的混合水凝胶已成为创新候选者，在再生医学、组织工程、药物输送装置、植入装置、生物传感和生物机器人领域具有多种应用。本文试图概括混合水凝胶的合成和表征方面的进展，并对其作为生物医学设备的功能和成功提供深入的见解。本文讨论了为目标生物医学应用而开发的碳纳米管-水凝胶混合系统的改进的比较性能和生物相容性。这篇综述的重点是对碳纳米管混合水凝胶的各种应用和局限性的最新更新。这将为理解基于碳纳米管的水凝胶及其在纳米治疗学中的应用提供一种整体方法。
更新日期：2018-02-01
中文翻译：
碳纳米管-水凝胶杂化物在纳米医学治疗中的进展
尽管水凝胶技术取得了显着进步，但机械强度低和缺乏导电性限制了其在骨骼肌、心脏和神经细胞的下一级生物医学应用。基于主客体化学的杂化纳米复合材料系统引起了人们的关注，因为它们完全克服了这些缺陷并产生具有可调节电气和机械特性的生物支架。近年来，基于碳纳米管（CNT）的混合水凝胶已成为创新候选者，在再生医学、组织工程、药物输送装置、植入装置、生物传感和生物机器人领域具有多种应用。本文试图概括混合水凝胶的合成和表征方面的进展，并对其作为生物医学设备的功能和成功提供深入的见解。本文讨论了为目标生物医学应用而开发的碳纳米管-水凝胶混合系统的改进的比较性能和生物相容性。这篇综述的重点是对碳纳米管混合水凝胶的各种应用和局限性的最新更新。这将为理解基于碳纳米管的水凝胶及其在纳米治疗学中的应用提供一种整体方法。
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