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Combinatorial Transcriptional Control of Plant Specialized Metabolism
Trends in Plant Science ( IF 20.5 ) Pub Date : 2018-01-31 , DOI: 10.1016/j.tplants.2017.12.006
Maite Colinas , Alain Goossens

Plants produce countless specialized compounds of diverse chemical nature and biological activities. Their biosynthesis often exclusively occurs either in response to environmental stresses or is limited to dedicated anatomical structures. In both scenarios, regulation of biosynthesis appears to be mainly controlled at the transcriptional level, which is generally dependent on a combined interplay of DNA-related mechanisms and the activity of transcription factors that may act in a combinatorial manner. How environmental and developmental cues are integrated into a coordinated cell type-specific stress response has only partially been unraveled so far. Building on the available examples from (metabolic) gene expression, here we propose theoretical models of how this integration of signals may occur at the level of transcriptional control.



中文翻译:

植物专门代谢的组合转录控制

植物会产生无数种具有不同化学性质和生物活性的特殊化合物。它们的生物合成通常仅响应于环境压力而发生,或仅限于专用的解剖结构。在这两种情况下,生物合成的调节似乎主要在转录水平上进行控制,这通常取决于DNA相关机制的相互作用和可能以组合方式起作用的转录因子的活性。到目前为止,如何部分地将环境和发育线索整合到特定于细胞类型的协调应激反应中。在(代谢)基因表达的可用示例的基础上,我们在此提出有关信号整合如何在转录控制水平上发生的理论模型。

更新日期:2018-01-31
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