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lncRNAs in Plant and Animal Sexual Reproduction
Trends in Plant Science ( IF 17.3 ) Pub Date : 2018-01-31 , DOI: 10.1016/j.tplants.2017.12.009
Agnieszka A. Golicz , Prem L. Bhalla , Mohan B. Singh

Long noncoding RNAs (lncRNAs) are transcripts over 200 base pairs in length with no discernible protein-coding potential. Multiple lines of evidence point to lncRNAs as master regulators, controlling the expression of protein-coding genes. Studies in plants and animals consistently show high expression of lncRNAs in reproductive organs in a cell- and tissue-specific manner. Sexual reproduction is a complex process that involves cell fate specification and specialized cell division requiring precise coordination of gene expression in response to intrinsic and extrinsic signals. The roles of lncRNAs as master regulators of gene expression and chromatin organization might make them particularly suited for coordination and control of molecular processes involved in sexual reproduction.



中文翻译:

动植物性繁殖中的lncRNA

长的非编码RNA(lncRNA)是长度超过200个碱基对的转录本,没有可识别的蛋白质编码潜能。多种证据表明,lncRNAs是主要调控因子,可控制蛋白质编码基因的表达。在植物和动物中的研究始终显示,lncRNA在细胞和组织特异性方式下在生殖器官中高表达。有性生殖是一个复杂的过程,涉及细胞命运的规范和专门的细胞分裂,需要对基因表达进行精确协调以响应内在和外在信号。lncRNA作为基因表达和染色质组织的主要调控者,可能使其特别适合于协调和控制涉及有性生殖的分子过程。

更新日期:2018-01-31
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