The 2 main options for the surgical management of breast cancer are breast-conserving surgery (BCS) with whole-breast irradiation (WBI) or mastectomy, together with some form of axillary staging. A 20-year follow-up of a randomized clinical trial comparing the 2 options showed no difference in overall survival.¹ Local recurrence in the ipsilateral breast was 14.3% in the group receiving BCS with WBI and 39.2% in those who did not receive radiotherapy.¹ Breast-conserving surgery with intraoperative radiotherapy has equivalent outcomes in patients with good prognostic features.²

中文翻译：

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乳腺癌随访期间的活检步骤与患者手术决策的关联

乳腺癌的外科手术治疗的两个主要选择是保乳手术（BCS）和全乳照射（WBI）或乳房切除术，以及某种形式的腋窝分期。对这2种选择进行比较的随机临床试验的20年随访结果显示，总生存期无差异。¹在接受WBI的BCS组中，同侧乳房的局部复发率为14.3％，而未接受放射治疗的组为39.2％。¹保留术中放疗的保乳手术在具有良好预后特征的患者中具有相同的结果。^2个