Recent advances in the field of infectious disease diagnostics have given rise to a number of host- and pathogen-centered diagnostic approaches. Most diagnostic approaches in contemporary infectious disease focus on pathogen detection and characterization. Host-focused diagnostics have recently emerged and are based on detecting the activation of biological pathways that are highly specific to the type of infecting pathogen (e.g., viral, bacterial, protozoan, fungal). Although this progress is encouraging, it is unlikely that any single diagnostic platform will fully address the clinician's need for actionable data with short turnaround times in all settings.

中文翻译：

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细菌感染和抗菌素耐药性的新分子诊断方法

传染病诊断领域的最新进展已引起许多以宿主和病原体为中心的诊断方法。当代传染病中的大多数诊断方法都集中在病原体的检测和表征上。最近出现了以宿主为中心的诊断方法，该方法基于检测对感染病原体类型（例如，病毒，细菌，原生动物，真菌）高度特异性的生物途径的激活。尽管这一进展令人鼓舞，但任何单一的诊断平台都不可能在所有情况下都以较短的周转时间完全满足临床医生对可操作数据的需求。