Encoding materials for programming a temporal sequence of actions,Journal of Materials Chemistry B

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Encoding materials for programming a temporal sequence of actions
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2018-01-29 00:00:00 , DOI: 10.1039/c7tb03215c
R. Jenjob _{1,

2,

3,

4,

5} , F. Seidi _{1,

2,

3,

4,

5} , D. Crespy _{1,

2,

3,

4,

5}

Affiliation

Materials are usually synthesized to allow a function that is either independent of time or that can be triggered in a specific environment. However in many cases, the materials experience different environments during their service and therefore they need to be adaptive so that useful functions are achieved during their lifecycle. New generation of materials need to be tailored to allow for a temporal sequence of reversible or irreversible responses in a cascade fashion. We discuss here strategies to encode a dynamic hierarchical structure of materials so that a temporal change of properties is created in different environments. Most of the examples are related to the sequenced release of drugs for combined therapy of cancer.

中文翻译：

编码材料，用于对动作的时间顺序进行编程

材料通常经过合成以允许独立于时间或可以在特定环境中触发的功能。但是，在许多情况下，材料在使用过程中会遇到不同的环境，因此，它们需要具有适应性，以便在其生命周期内实现有用的功能。需要定制新一代材料，以允许级联方式的可逆或不可逆响应的时间顺序。我们在这里讨论对材料的动态分层结构进行编码的策略，以便在不同的环境中创建属性的时间变化。大多数例子与用于癌症联合治疗的药物的顺序释放有关。

更新日期：2018-01-29

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