A Phytol‐Enriched Diet Activates PPAR‐α in the Liver and Brown Adipose Tissue to Ameliorate Obesity‐Induced Metabolic Abnormalities,Molecular Nutrition & Food Research

当前位置： X-MOL 学术 › Mol. Nutr. Food Res. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A Phytol‐Enriched Diet Activates PPAR‐α in the Liver and Brown Adipose Tissue to Ameliorate Obesity‐Induced Metabolic Abnormalities
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2018-02-22 , DOI: 10.1002/mnfr.201700688
Ji-Yeong An ₁ , Huei-Fen Jheng ₁ , Hiroyuki Nagai _{1,

2} , Kohei Sanada ₁ , Haruya Takahashi ₁ , Mari Iwase ₁ , Natsumi Watanabe ₁ , Young-Il Kim ₁ , Aki Teraminami ₁ , Nobuyuki Takahashi _{1,

3} , Rieko Nakata ₄ , Hiroyasu Inoue ₄ , Shigeto Seno ₅ , Hideo Mastuda ₅ , Teruo Kawada _{1,

3} , Tsuyoshi Goto _{1,

3}

Affiliation

Peroxisome proliferator‐activated receptor alpha (PPAR‐α) is a ligand‐activated transcription factor that regulates lipid and carbohydrate metabolism. We investigate the effects of naturally occurring PPAR‐α agonists, phytol, and its metabolite phytanic acid, on obesity‐induced metabolic disorders using a mouse model.

中文翻译：